Scientific development fields of interest

MOLECULAR MECHANISMS OF CARDIOVASCULAR DISEASES

The research programs focus on (among others):

• Detecting mutations in patients with cardiomyopathies, secondary hypertension;
• Assessing polymorphisms of known genes in premature atherosclerosis in women, in cardiomyopathies, and severe heart failure;
• Analyzing explanted heart tissue in dilated and ischemic cardiomyopathies.

CORONARY ARTERY DISEASE

The research mainly focuses on:

• Studies on the vulnerable atherosclerotic plaque;
• Therapeutic angiogenesis with the use genes for VEGF and FGF administered subcutaneously in 'no option patients';
• Assessing the efficacy and safety of using intracoronary autologous bone marrow transplantations in treating patients with early post-infarction left ventricular dysfunction;
• Influenza vaccination in acute cardiac event prevention.

FINDING AND VERIFYING NEW METHODS FOR NONINVASIVE DIAGNOSTICS OF HEART DISEASES

The main interests include:

• Using modern echocardiographic techniques and technologies in the diagnosis and quantitative evaluation of primary and secondary myocardium pathologies;
• Assessing the sensitivity and specificity of 64-clice CT scans in noninvasive coronarography in patients with acquired valvular diseases qualified for surgical repair;
• Assessing the usefulness of the Doppler method to visualize the renal arteries and abdominal aorta in patients who have undergone a surgical repair for Type-A aortic dissection.

ELECTROPHYSIOLOGICAL STUDIES AND NON-PHARMACOLOGICAL TREATMENT OF ARRHYTHMIA

Our researchers focus on:

• Identifying mechanisms and factors predisposing patients to focal atrial fibrillation;
• Improving the methods of diagnostics and electrotherapy of supraventricular and ventricular arrhythmias;
• Evaluating the natural history in patients with recurrent tachyarrhythmia;
• Preparing optimal methods of qualifying for and evaluating the efficacy of the resynchronizing stimulation therapy.

ACQUIRED AND CONGENITAL HEART DISEASE

Research is mainly focused on:

• Interventional treatment of congenital and acquired heart disease;
• Biomarkers importance in monitoring acquired heart disease;
• Evaluating methods of molecular biology in diagnostics of infective endocarditis.

HEART FAILURE

Research programs focus on:

• Improving care for patients with severe heart failure, and assessing and optimizing indications for heart transplantation;
• Treating severe heart failure with artificial heart ventricles;
• Treating post-infarction left ventricle aneurysms with Menicanti method
• Biomarkers importance in patients with severe heart failure;
• Dilated cardiomyopathy etiopathogenesis.

ARTERIAL HYPERTENSION

Research is mainly focused on:

• High-specialty diagnostics of secondary arterial hypertension;
• Follow-up hypertensive patients who have undergone repair surgery for thoracic aortic dissection;
• Assessing the clinical significance of blood pressure changes measured non-invasively;
• Assessing the clinical significance of sleep disturbances in hypertensive patients and how these disturbances coincide with blood pressure changes.

CARDIOSURGERY

Research programs focus on:

• Treating valvular disease by implanting non-stent valves and homografts;
• Minimally invasive treatment of coronary artery disease;
• Surgical treatment of aorta diseases (hybrid surgery);
• Assessing how brain oxygenation influences the neurological condition of patients who have undergone cardiosurgery;
• Analyzing quality of life of patients after surgery for congenital heart disease.

EPIDEMIOLOGY, HEALTH PROMOTION AND CARDIOLOGIC RAHABILITATION

Research studies include:

• Evaluating the knowledge, attitude and skills of health professionals (including nurses) in health promotion, cardiovascular diseases prevention;
• Monitoring determinants of cardiovascular diseases, how well they are controlled, and their time trends; coincidence with morbidity and mortality;
• Prevalence of cardiovascular disease classic and new risk factors in Polish population;
• Applying telemedicine in cardiac diagnostics and rehabilitation;
• Adjusting the form of physical training to therapy progress (primary angioplasty, cardioverter-defibrillator, synchronic therapy);
• Non-invasive evaluation of the autonomic system as the indicator of complex cardiologic rehabilitation efficacy.